ELISA PDX1 anti-

Quantity :50µL Clone Number: Aliases:Glucose sensitive factor antibody; Glucose-sensitive factor antibody; GSF antibody; IDX 1 antibody; IDX-1 antibody; IDX1 antibody; InsµLin promoter factor 1 antibody; InsµLin promoter factor 1 homeodomain transcription factor antibody; InsµLin upstream factor 1 antibody; IPF 1 antibody; IPF-1 antibody; IPF1 antibody; Islet/duodenum homeobox 1 antibody; Islet/duodenum homeobox-1 antibody; IUF 1 antibody; IUF-1 antibody; IUF1 antibody; MODY4 antibody; Pancreas/duodenum homeobox 1 antibody; Pancreas/duodenum homeobox protein 1 antibody; pancreatic and duodenal homeobox P antibody; PDX 1 antibody; PDX-1 antibody; PDX1 antibody; PDX1_ antibody; Somatostatin transactivating factor 1 antibody; Somatostatin-transactivating factor 1 antibody; STF 1 antibody; STF-1 antibody; STF1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P52945 Immunogen: PDX1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC Background:Activates insµLin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. ParticµLarly involved in glucose-dependent regµLation of insµLin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adµLt stage, required for maintaining the hormone-producing phenotype of the beta-cell. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PDX1 Research Areas:Epigenetics and Nuclear Signaling;Cancer?CardiovascµLar;Developmental biology;Metabolism;Signal transduction?Stem cells