ELISA NRCAM Antibody, HRP

Quantity :50µg Clone Number: Aliases:Bravo antibody; hBravo antibody; Neuronal cell adhesion molecµLe antibody; Neuronal surface protein Bravo antibody; Ng CAM related antibody; Ng-CAM-related antibody; NgCAM related cell adhesion molecµLe antibody; NgCAM-related cell adhesion molecµLe antibody; Nr CAM antibody; Nr-CAM antibody; Nrcam antibody; NRCAM_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92823 Immunogen:Recombinant Neuronal cell adhesion molecµLe protein (1194-1299AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NRCAM Research Areas:Neuroscience