ELISA NCOA1 Antibody, FITC

Quantity :50µg Clone Number: Aliases:bHLHe74 antibody; Class E basic helix-loop-helix protein 74 antibody; F SRC 1 antibody; Hin 2 protein antibody; Hin2 protein antibody; MGC129719 antibody; MGC129720 antibody; mNRC 1 antibody; NCoA 1 antibody; NCoA-1 antibody; Ncoa1 antibody; NCOA1_ antibody; Nuclear receptor coactivator 1 antibody; Nuclear receptor coactivator protein 1 antibody; NY REN 52 antigen antibody; Protein Hin 2 antibody; Protein Hin-2 antibody; Protein Hin2 antibody; Renal carcinoma antigen NY REN 52 antibody; Renal carcinoma antigen NY-REN-52 antibody; RIP 160 antibody; RIP160 antibody; SRC 1 antibody; SRC-1 antibody; Steroid receptor coactivator 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15788 Immunogen:Recombinant Nuclear receptor coactivator 1 protein (284-393AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Nuclear receptor coactivator that directly binds nuclear receptors and stimµLates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating mµLtisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NCOA1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction