ELISA ACOD1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:ACOD1 antibody; Aconitate decarboxylase 1 antibody; Aconitate decarboxylase antibody; CAD antibody; Cis aconitate decarboxylase antibody; Immune responsive gene 1 protein homolog antibody; Immune-responsive gene 1 protein homolog antibody; Immunoresponsive 1 homolog (mouse) antibody; Irg1 antibody; IRG1_ antibody; OC116 antibody; OPTB1 antibody; TCTIRC7 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:A6NK06 Immunogen:Recombinant Cis-aconitate decarboxylase protein (57-257AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Involved in the inhibition of the inflammatory response. Acts as a negative regµLator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimµLating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ACOD1 Research Areas:Immunology; Metabolism; Signal transduction