ELISA Acetyl-H2AFZ (K11) anti-

Quantity :50µL Clone Number: Aliases:H2A histone family member Z antibody; H2A.z antibody; H2A/z antibody; H2afz antibody; H2AZ antibody; H2AZ_ antibody; Histone H2A.Z antibody; MGC117173 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P0C0S5 Immunogen:Peptide sequence around site of Acetyl-Lys (11) derived from Histone H2A.Z Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IF, ChIP; Recommended dilution: WB:1:200-1:2000, IF:1:50-1:200 Background:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellµLar machineries which require DNA as a template. Histones thereby play a central role in transcription regµLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regµLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:H2AFZ Research Areas:Epigenetics and Nuclear Signaling