ELISA TPMT Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:HGNC:12014 antibody; S adenosyl L methionine thiopurine S methyltransferase antibody; Thiopurine methyltransferase antibody; Thiopurine S methyltransferase antibody; Thiopurine S-methyltransferase antibody; TPMT antibody; TPMT_ antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P51580
Immunogen:Recombinant Thiopurine S-methyltransferase protein (4-244AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:TPMT is an enzyme that metabolizes thiopurine drµgs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drµgs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drµgs within individuals. A pseudogene for this locus is located on chromosome 18q.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:TPMT
Research Areas:Metabolism; Signal transduction
Internal Reference:
CSB-PA00585D0Rb
Website URL:
/shop/csb-pa00585d0rb-elisa-tpmt-antibody-biotin-177953
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