ELISA Recombinant Fibroblast growth factor 7 protein(FGF7) (Active)

Quantity:100µg. Research Areas:Cancer Uniprot NO.:P21781 Uniprot Entry Name:FGF7_ Gene Names:FGF7,KGF Species:Homo sapiens () Source:E.Coli Expression Region:32-194aa Sequence:CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:18.9 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 10 ng/mL, corresponding to a specific activity of ? 1.0 × 105 IU/mg. Purity:>96% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, 0.5 M NaCl, pH 8.0 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:FGF-7, HBGF-7, Keratinocyte growth factor Relevance:Plays an important role in the regµLation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:8663044}. PubMed ID:2475908; 1664700; 14702039; 16572171; 15489334; 2915979; 8663044; 15806171; 16597617; 20094046 Function:Plays an important role in the regµLation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Involvement in disease: SubcellµLar Location:Secreted Protein Families:Heparin-binding growth factors family Tissue Specificity:Epithelial cell. Paythway:MAPKsignalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3685 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=567268 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:2252 STRING Database Link:https://string-db.org/network/9606.ENSP00000267843 OMIM Database Link:https://www.omim.org/entry/148180148180148180