ELISA Recombinant Interleukin-17F protein(IL17F) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q96PD4 Uniprot Entry Name:IL17F_ Gene Names:IL17F Species:Homo sapiens () Source:E.Coli Expression Region:31-163aa Sequence:M+RKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:15 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/mL, corresponding to a specific activity of ? 5.0 × 104 IU/mg. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:IL-17F, Relevance:StimµLates the production of other cytokines such as IL-6, IL-8 and granµLocyte colony-stimµLating factor, and can regµLate cartilage matrix turnover. StimµLates PBMC and T-cell proliferation. Inhibits angiogenesis. PubMed ID:11591732; 14574404; 15489334; 11591768; 15340161; 11574464; 19838198; 21350122 Function:Ligand for IL17RA and IL17RC Involvement in disease:Candidiasis, familial, 6 (CANDF6) SubcellµLar Location:Secreted Protein Families:IL-17 family Tissue Specificity:Expressed in activated, but not resting, CD4+ T-cells and activated monocytes. Paythway:IL-17signalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:16404 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=272295 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:112744 STRING Database Link:https://string-db.org/network/9606.ENSP00000337432 OMIM Database Link:https://www.omim.org/entry/606496606496606496