ELISA Recombinant Interleukin-17B protein(IL17B) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q9UHF5 Uniprot Entry Name:IL17B_ Gene Names:IL17B,IL20,NIRF,ZCYTO7,UNQ516/PRO1031 Species:Homo sapiens () Source:E.Coli Expression Region:21-180aa Sequence:M+QPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:18.3 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by inducing IL-8 secretion of HepG2 cells is less than 1.0 ?g/mL, corresponding to a specific activity of ? 1000 IU/mg. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4, with 0.1 % Tween-20 and 3 % Trehalose Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:IL-17B, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, Relevance:StimµLates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. PubMed ID:10749887; 10639155; 12975309; 15489334 Function:StimµLates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Involvement in disease: SubcellµLar Location:Secreted Protein Families:IL-17 family Tissue Specificity:Expressed in adµLt pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary. Paythway:IL-17signalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:5982 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=156979 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:27190 STRING Database Link:https://string-db.org/network/9606.ENSP00000261796 OMIM Database Link:https://www.omim.org/entry/604627604627604627