3diag - C1Q - Tia Kit

Kit for determination of C1q level on routine biochemical analyzers. The kit includes a reagent, a calibrator and a control. Congenital C1q deficiency is extremely rare (several dozen cases where most patients suffered from systemic lupus erythematosus (SLE)). Sometimes the acquired deficiency is caused by the presence of anti-C1q autoantibodies. Its deficiency has a significant effect on the host's defense mechanisms and on the elimination of immune complexes. It is usually associated with a high incidence of autoimmune and infectious diseases (systemic lupus (SLE), glomerulonephritis, polymyositis, etc.). Measurement of C1q is key to distinguishing between hereditary and acquired angioedema, as normal levels are found in hereditary angioedema, while decreased levels occur in acquired angioedema. Applications for commonly used biochemical analyzers available (Advia®, Alinity C, AU®, Atellica™, cobas® C, Optilite®, Mindray and others).