ELISA TLR2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to s and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecµLes derived from microorganisms known as pathogen-associated molecµLar patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regµLation of signaling pathways to modµLate the host's inflammatory response. This gene is also thoµght to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing resµLts in mµLtiple transcript variants. Immunogen:Toll-like receptor 2 Synonyms:CD282, TIL4, TLR2 Observed MW:105 kDa Uniprot ID:O60603 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200 Gene ID: Research Area: