ELISA VPS8 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopµLations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).
Immunogen:vacuolar protein sorting 8 homolog(S. cerevisiae)
Synonyms:FLJ32099, KIAA0804, VPS8
Observed MW:151 kDa
Uniprot ID:Q8N3P4
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IF,IP
Recommended dilution:WB: 1:500-1:5000?IP: 1:200-1:2000; IF: 1:10-1:100
Gene ID:23355
Research Area:Signal Transduction
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Référence interne:
FNab09451
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