ELISA VEGFR-1|FLT-1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes a member of the vascµLar endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellµLar ligand-binding region with seven immunoglobµLin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vascµLogenesis. Expression of this receptor is found in vascµLar endothelial cells, placental trophoblast cells and peripheral blood monocytes. MµLtiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a fµLl-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. Immunogen:fms-related tyrosine kinase 1 (vascµLar endothelial growth factor/vascµLar permeability factor receptor) Synonyms:FLT, FLT 1, FLT1, FLT-1, Fms like tyrosine kinase 1, FRT, sflt1, Tyrosine protein kinase FRT, VEGF receptor 1, VEGFR 1, VEGFR1, VEGFR-1 Observed MW:151 kDa Uniprot ID:P17948 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 Gene ID:2321 Research Area:Signal Transduction, Metabolism, CardiovascµLar, Immunology, Developmental biology