ELISA UXT anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Involved in gene transcription regµLation. Acts in concert with the corepressor URI1 to regµLate androgen receptor transcription(AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation(PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a mµLtidomain organizer that potentially integrates mitochondria and the microtubµLar cytoskeleton with chromosome remodeling(PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially throµgh its association with LRPPRC(PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function(PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimµLatory factors like MECOM(PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region. Immunogen:ubiquitously-expressed transcript Synonyms:ART 27, Protein UXT, UXT Observed MW: Uniprot ID:Q9UBK9 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IP Recommended dilution:WB: 1:200-1:1000; IP: 1:200-1:1000 Gene ID:8409 Research Area:Metabolism