ELISA USP37 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2). Immunogen:ubiquitin specific peptidase 37 Synonyms:Deubiquitinating enzyme 37, KIAA1594, Ubiquitin thiolesterase 37, USP37 Observed MW:110 kDa,70 kDa Uniprot ID:Q86T82 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:5000; IP: 1?200-1?2000 Gene ID:57695 Research Area:Epigenetics, Metabolism