ELISA USP14 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticµLum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticµLum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscµLar junctions(NMJs). Immunogen:ubiquitin specific peptidase 14(tRNA-guanine transglycosylase) Synonyms:Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14 Observed MW:52-60 kDa Uniprot ID:P54578 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF, FC Recommended dilution:WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100 Gene ID:9097 Research Area:Epigenetics, Metabolism