ELISA uPA anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellµLar matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellµLar space by plasminogen activator inhibitor-1(PAI-1), which is stored in the extracellµLar matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder(QPD). Immunogen:plasminogen activator, urokinase Synonyms:ATF, PLAU, U plasminogen activator, uPA, URK Observed MW:54 kDa Uniprot ID:P00749 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP, IF Recommended dilution:WB: 1:500-1:1000; IHC?1:20-1:200?IF: 1?20-1?200; IP: 1?500-1?2000 Gene ID:5328 Research Area:Immunology, CardiovascµLar, Signal Transduction