ELISA UNC5C-Specific anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:UNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repµLsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repµLsion in growth cones may be caused by its association with DCC that may trigger signaling for repµLsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C. Immunogen:unc-5 homolog C(C. elegans) Synonyms:UNC5C, unc 5 homolog C(C. elegans), UNC5H3, Protein unc 5 homolog 3, Protein unc 5 homolog C Observed MW:103 kDa Uniprot ID:O95185 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:5000 Gene ID: Research Area:Signal Transduction, Developmental biology