ELISA UNC13A|Munc13-1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granµLe priming in insµLin secretion. The antibody is specific to UNC13A. Immunogen:unc-13 homolog A(C. elegans) Synonyms:KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A Observed MW:193 kDa Uniprot ID:Q9UPW8 Reactivity:, Mouse Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:5000; IP: 1?200-1?2000 Gene ID: Research Area:Neuroscience, Signal Transduction