ELISA UBR2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:E3 ubiquitin-protein ligase which is a component of the N-end rµLe pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rµLe, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regµLator of the leucine-mTOR signaling pathway, thereby controlling cell growth. Immunogen:ubiquitin protein ligase E3 component n-recognin 2 Synonyms:BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2 Observed MW:66 kDa Uniprot ID:Q8IWV8 Reactivity:, Mouse Tested Application:ELISA, WB, IF, IHC Recommended dilution:WB: 1:200-1:2000; IF?1?10-1:100; IHC: 1:20-1:200 Gene ID:23304 Research Area:Epigenetics, Metabolism, Developmental biology