ELISA TTRAP anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA throµgh hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regµLator of ETS1 and inhibit nuclear factor-kappa-B activation. Immunogen:TRAF and TNF receptor associated protein Synonyms:5 Tyr DNA phosphodiesterase, AD022, dJ30M3.3, EAP2, EAPII, ETS1 associated protein 2, ETS1 associated protein II, TDP2, TTRAP, Tyr DNA phosphodiesterase 2 Observed MW:44 kDa Uniprot ID:O95551 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IP Recommended dilution:WB: 1:500-1:5000; IP: 1:200-1:2000 Gene ID: Research Area:Signal Transduction