ELISA TRIM63 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. RegµLates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. RegµLates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regµLating an anti-hypertrophic PKC-mediated signaling pathway. May regµLate the organization of myofibrils throµgh TTN in muscle cells.
Immunogen:tripartite motif-containing 63
Synonyms:FLJ32380, IRF, Iris RING finger protein, MuRF 1, MURF1, MURF2, RING finger protein 28, RNF28, SMRZ, TRIM63, tripartite motif containing 63
Observed MW:40 kDa
Uniprot ID:Q969Q1
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Gene ID:84676
Research Area:Epigenetics, CardiovascµLar, Metabolism, Signal Transduction
Référence interne:
FNab08992
URL de site web:
/shop/fnab08992-elisa-trim63-anti-178805
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