ELISA TNIP2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regµLates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimµLus-and cell type specific. Required for stability of MAP3K8. Involved in regµLation of apoptosis in endothelial cells; promotes TEK agonist-stimµLated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes. Immunogen:TNFAIP3 interacting protein 2 Synonyms:ABIN2, FLIP1 Observed MW:50 kDa Uniprot ID:Q8NFZ5 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:79155 Research Area:CardiovascµLar, Signal Transduction