ELISA STIM2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellµLar Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticµLum which activates both store-operated and store-independent Ca(2+)-influx. RegµLates basal cytosolic and endoplasmic reticµLum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticµLum Ca(2+) concentration, translocates from the endoplasmic reticµLum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+)(CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. Immunogen:stromal interaction molecµLe 2 Synonyms:KIAA1482 Observed MW:85-115 kDa Uniprot ID:Q9P246 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, IP, WB Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 Gene ID:57620 Research Area:Neuroscience, Immunology