ELISA SSX2IP anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions(AJs). May connect the nectin-afadin and E-cadherin-catenin system throµgh alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs throµgh afadin and alpha-actinin(By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling(By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubµLe nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regµLator of spindle anchoring at the mitotic centrosome(PubMed:23816619, PubMed:26545777). Involved in ciliogenesis(PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia(PubMed:24356449). Immunogen:synovial sarcoma, X breakpoint 2 interacting protein Synonyms:KIAA0923 Observed MW:64 kDa Uniprot ID:Q9Y2D8 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:117178 Research Area:Cancer, Metabolism