ELISA SMYD2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4'(H3K4me) and dimethylates histone H3 'Lys-36'(H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regµLation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. Immunogen:SET and MYND domain containing 2 Synonyms:KMT3C Observed MW:50 kDa Uniprot ID:Q9NRG4 Reactivity:, Mouse Tested Application:ELISA, WB, IF, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:56950 Research Area:Epigenetics