ELISA SLC22A1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Translocates a broad array of organic cations with various structures and molecµLar weights including the model compounds 1-methyl-4-phenylpyridinium(MPP), tetraethylammonium(TEA), N-1-methylnicotinamide(NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium(ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drµgs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium(TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubµLar epithelial cells. The choline transport is activated by MMTS. RegµLated by various intracellµLar signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodµLin complex, the calmodµLin-dependent kinase II and LCK tyrosine kinase. Immunogen:solute carrier family 22(organic cation transporter), member 1 Synonyms:OCT1 Observed MW:61-67 kDa Uniprot ID:O15245 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:6580 Research Area:Stem Cells