ELISA SLC12A5-Specific anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:KCC2, encoded by SLC12A5, is a neuron-specific K+-Cl-cotransporter that is essential for Cl-homeostasis and inhibitory synaptic transmission in brain. KCC2 is expressed at high levels in neurons throµghout the nervous system. KCC2 deletion caused animal death. Alterations of KCC2 have been linked to neuropathic pain, temporal lobe epilepsy, and other diseases. This antibody can detect ~130 kda monomer and ~250 kDa dimer of KKC2 in brain lysate. Immunogen:solute carrier family 12(potassium-chloride transporter), member 5 Synonyms:hKCC2, K Cl cotransporter 2, KCC2, KIAA1176, Neuronal K Cl cotransporter, SLC12A5 Observed MW:126 kDa Uniprot ID:Q9H2X9 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200 Gene ID: Research Area:Signal Transduction