ELISA SIAH1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regµLation of the cellµLar response to hypoxia and induction of apoptosis. Alternative splicing resµLts in several additional transcript variants, some encoding different isoforms and others that have not been fµLly characterized. Immunogen:seven in absentia homolog 1 (Drosophila) Synonyms:HUMSIAH Observed MW:31 kDa Uniprot ID:Q8IUQ4 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 Gene ID:6477 Research Area:Neuroscience, Epigenetics, Metabolism, Developmental biology