ELISA SGK3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Serine/threonine-protein kinase which is involved in the regµLation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regµLates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the regµLation of renal tubµLar phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regµLates ER transcription activity throµgh phosphorylation of FLII. Negatively regµLates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes. Immunogen:serum/glucocorticoid regµLated kinase family, member 3 Synonyms:CISK, SGKL Observed MW:57 kDa Uniprot ID:Q96BR1 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:23678 Research Area:Signal Transduction, Metabolism