ELISA SEPT2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubµLes, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubµLin. Required for the progression throµgh mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regµLating the assembly of the tectonic-like complex(also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellµLar microbial pathogens, Listeria monocytogenes and Shigella flexneri. Immunogen:septin 2 Synonyms:hNedd5, NEDD 5, NEDD5, SEPT2, SEPT2/septin 2, septin 2, septin2 Observed MW:45 kDa Uniprot ID:Q15019 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, IP, IF, WB, FC Recommended dilution:WB: 1:500-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:4735 Research Area:Cell Division and Proliferation, Metabolism