ELISA SENP3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjµgates. Deconjµgates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjµgates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing throµgh deconjµgation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regµLation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Immunogen:SUMO1/sentrin/SMT3 specific peptidase 3 Synonyms:SSP3, SUSP3 Observed MW:65-70 kDa Uniprot ID:Q9H4L4 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:2000 Gene ID:26168 Research Area:Metabolism