ELISA SOX2 anti-

Quantity :50µL Clone Number:2E1 Aliases:Transcription factor SOX-2, SOX2 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P48431 Immunogen:A syntheQuantityd peptide derived from SOX2 Raised in: Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 Background:Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SOX2 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Developmental biology; Signal transduction; Stem cells