ELISA SLC16A1 anti-

Quantity :50µL Clone Number:9D12 Aliases:Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1), SLC16A1, MCT1 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P53985 Immunogen:A syntheQuantityd peptide derived from Monocarboxylic acid transporter 1 Raised in: Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 Background:Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellµLar responses to a high-fat diet by modµLating the cellµLar levels of lactate and pyruvate, small molecµLes that contribute to the regµLation of central metabolic pathways and insµLin secretion, with concomitant effects on plasma insµLin levels and blood glucose homeostasis. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC16A1 Research Areas:Cancer; Metabolism; Signal transduction