ELISA SDHB anti-

Quantity :50µL Clone Number: Aliases:CWS2 antibody; DHSB_ antibody; FLJ92337 antibody; Ip antibody; Iron sµLfur subunit antibody; Iron sµLfur subunit of complex II antibody; Iron-sµLfur subunit of complex II antibody; mitochondrial antibody; PGL 4 antibody; PGL4 antibody; SDH 1 antibody; SDH antibody; SDH1 antibody; SDH2 antibody; SDH2, homolog of antibody; SdhB antibody; SDHIP antibody; Succinate dehydrogenase [ubiquinone] iron sµLfur protein mitochondrial antibody; Succinate dehydrogenase [ubiquinone] iron sµLfur subunit antibody; Succinate dehydrogenase [ubiquinone] iron-sµLfur subunit antibody; succinate dehydrogenase [ubiquinone] iron-sµLfur subunit, mitochondrial antibody; Succinate Dehydrogenase 1 Iron SµLfur Subunit antibody; Succinate Dehydrogenase 2, S. cerevisiae, homolog of antibody; Succinate dehydrogenase complex iron sµLfur subunit B antibody; Succinate dehydrogenase complex subunit B iron sµLfur antibody; Succinate Dehydrogenase Complex Subunit B Iron SµLfur Protein antibody; succinate dehydrogenase complex, subunit B, iron sµLfur (Ip) antibody; Succinate dehydrogenase iron sµLfur protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P21912 Immunogen:Synthetic peptide of SDHB Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 Background:Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sµLfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sµLfur centers of the enzyme. Sporadic and familial mutations in this gene resµLt in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SDHB Research Areas:Cancer;Cell biology;Metabolism;Signal transduction