ELISA SRY anti-

Quantity :100µL Clone Number: Aliases:Essential protein for sex determination in males antibody; Sex determining region on Y antibody; Sex determining region protein antibody; Sex determining region Y antibody; Sex-determining region Y protein antibody; sox21b antibody; SRXX1 antibody; SRXY1 antibody; SRY 1 antibody; SRY antibody; SRY_ antibody; Sry1 antibody; Sry3BI antibody; SRYGENE antibody; TDF antibody; TDY antibody; Testis determining factor antibody; Testis Determining Factor on Y antibody; Testis-determining factor antibody; Transcription factor Sox-21-B antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q05066 Immunogen:SyntheQuantityd peptide derived from internal of SRY. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Transcriptional regµLator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granµLosa cells By similarity. In male adµLt brain involved in the maintenance of motor functions of dopaminergic neurons By similarity. Involved in different aspects of gene regµLation including promoter activation or repression By similarity. Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. Sinclair A.H., Nature 346:240-244(1990). Su H., Am. J. Hum. Genet. 52:24-38(1993). Behlke M.A., Genomics 17:736-739(1993). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SRY Research Areas:Epigenetics and Nuclear Signaling;Developmental biology