ELISA TNFRSF1B anti-

Quantity :100µL Clone Number: Aliases:CD120b antibody; p75 antibody; p75 TNF receptor antibody; p75TNFR antibody; p80 TNF alpha receptor antibody; p80 TNF-alpha receptor antibody; Soluble TNFR1B variant 1 antibody; TBP-2 antibody; TBPII antibody; TNF R II antibody; TNF R2 antibody; TNF R75 antibody; TNF-R2 antibody; TNF-RII antibody; TNFBR antibody; TNFR-II antibody; TNFR1B antibody; TNFR2 antibody; TNFR80 antibody; TNFRII antibody; Tnfrsf1b antibody; TNR1B_ antibody; Tumor necrosis factor beta receptor antibody; Tumor necrosis factor binding protein 2 antibody; Tumor necrosis factor receptor 2 antibody; Tumor necrosis factor receptor superfamily member 1B antibody; Tumor necrosis factor receptor type II antibody; Tumor necrosis factor-binding protein 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P20333 Immunogen:SyntheQuantityd peptide derived from C-terminal of TNF Receptor II. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500 Background:Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which sµggests that it regµLates TNF-alpha function by antagonizing its biological activity. Smith C.A., Science 248:1019-1023(1990). Kohno T., Proc. Natl. Acad. Sci. U.S.A. 87:8331-8335(1990). Beltinger C.P., Genomics 35:94-100(1996). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNFRSF1B Research Areas:Cancer;Cell biology;Immunology;Signal transduction