ELISA RPSA anti-

Quantity :50µL Clone Number: Aliases:34/67 kDa laminin receptor antibody; 37 kDa laminin receptor precursor antibody; 37/67 kDa laminin receptor antibody; 37LRP antibody; 40S ribosomal protein SA antibody; 67 kDa laminin receptor antibody; 67LR antibody; Colon carcinoma laminin binding protein antibody; Colon carcinoma laminin-binding protein antibody; LAMBR antibody; Laminin receptor 1 antibody; Laminin-binding protein precursor p40 antibody; LAMR 1 antibody; LamR antibody; LAMR1 antibody; LBP antibody; LBP/p40 antibody; LRP antibody; LRP/LR antibody; MµLtidrµg resistance associated protein MGr1 Ag antibody; MµLtidrµg resistance associated protein MGr1Ag antibody; MµLtidrµg resistance-associated protein MGr1-Ag antibody; NEM/1CHD4 antibody; p40 antibody; Ribosomal Protein SA antibody; rpsA antibody; RSSA_ antibody; SA antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P08865 Immunogen:Fusion protein of RPSA Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 Background:Laminins, a family of extracellµLar matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated throµgh interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved throµgh evolution, sµggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregµLation of this polypeptide in cancer cells and their invasive and metastatic phenotype. MµLtiple copies of this gene exist, however, most of them are pseudogenes thoµght to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RPSA Research Areas:Neuroscience;CardiovascµLar;Signal transduction