ELISA SNCB anti-

Quantity :100µL Clone Number: Aliases:14 kDa brain-specific protein antibody; Beta-synuclein antibody; Phosphoneuroprotein 14 antibody; PNP14 antibody; Sncb antibody; Synuclein beta antibody; SYUB_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q16143 Immunogen:SyntheQuantityd peptide derived from Synuclein ? antibody. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 Background:Non-amyloid component of senile plaques found in Alzheimer disease. CoµLd act as a regµLator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimµLated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011. Makoto Hashimoto, J. Biol. Chem., May 2004; 279: 23622 - 23629. Cristine Alves da Costa, J. Biol. Chem., Sep 2003; 278: 37330 - 37335. Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SNCB Research Areas:Neuroscience