ELISA ADAM10 anti-

Quantity :50µL Clone Number: Aliases:A disintegrin and metalloprotease domain 10 antibody; A disintegrin and metalloproteinase domain 10 antibody; AD 10 antibody; AD10 antibody; AD18 antibody; ADA10_ antibody; ADAM 10 antibody; ADAM metallopeptidase domain 10 antibody; ADAM10 antibody; CD 156c antibody; CD156c antibody; CD156c antigen antibody; CDw156 antibody; disintegrin and metalloproteinase domain containing protein 10 antibody; Disintegrin and metalloproteinase domain-containing protein 10 antibody; HsT 18717 antibody; HsT18717 antibody; Kuz antibody; Kuzbanian antibody; Kuzbanian protein homolog antibody; Kuzbanian; Drosophila; homolog of antibody; MADM antibody; Mammalian disintegrin metalloprotease antibody; Mammalian disintegrin-metalloprotease antibody; RAK antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14672 Immunogen:Fusion protein of ADAM10 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 Background:Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regµLated alpha-secretase cleavage of amyloid precursor protein (APP). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ADAM10 Research Areas:Cancer;Cell biology;Signal transduction