ELISA DTX2 anti-

Quantity :50µL Clone Number: Aliases:Deltex 2 antibody; deltex homolog 2 (Drosophila) antibody; deltex; Drosophila; homolog of; 2 antibody; Deltex2 antibody; DTX2 antibody; DTX2_ antibody; hDTX2 antibody; Highly similar to hPMSR6 [H.sapiens] antibody; KIAA1528 antibody; Probable E3 ubiquitin-protein ligase DTX2 antibody; Protein deltex 2 antibody; Protein deltex-2 antibody; RING finger protein 58 antibody; RNF58 antibody; Zinc ion binding protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86UW9 Immunogen:Fusion protein of DTX2 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50 Background:DTX2 functions as an E3 ubiquitin ligase. RegµLator of Notch signaling, a signaling pathway involved in cell-cell communications that regµLates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regµLator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, sµggesting that it may regµLate the Notch pathway via some ubiquitin ligase activity. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DTX2 Research Areas:Stem cells