ELISA ING4 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Brain my036 protein antibody; Candidate tumor suppressor p33 ING 1 homolog antibody; Candidate tumor suppressor p33 ING1 homolog antibody; D6Wsu147e antibody; D6Xrf92 antibody; ING 1 like protein antibody; ING 4 antibody; ING1 like protein antibody; ING4 antibody; ING4_ antibody; Inhibitor of growth family member 4 antibody; Inhibitor of growth family member 4 long isoform antibody; Inhibitor of growth protein 4 antibody; MGC12557 antibody; my036 antibody; p29 ING 4 antibody; p29 ING4 antibody; p29ING4 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UNL4 Immunogen:Recombinant Inhibitor of growth protein 4 protein (75-249AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bµLk of histone H4 acetylation in vivo. Throµgh chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modµLating the transcriptional output of signaling pathways which regµLate cell proliferation. Can suppress brain tumor angiogenesis throµgh transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ING4 Research Areas:Epigenetics and Nuclear Signaling; Cancer