ELISA ZNRF3 anti-

Quantity :50µg Clone Number: Aliases:ZNRF3 antibody; KIAA1133 antibody; RNF203 antibody; E3 ubiquitin-protein ligase ZNRF3 antibody; EC 2.3.2.27 antibody; RING finger protein 203 antibody; RING-type E3 ubiquitin transferase ZNRF3 antibody; Zinc/RING finger protein 3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9µLT6 Immunogen:Recombinant E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200 Background:E3 ubiquitin-protein ligase that acts as a negative regµLator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the Quantity of the intestinal stem cell zone. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ZNRF3 Research Areas:Epigenetics and Nuclear Signaling