ELISA SOX17 Antibody, HRP

Quantity :50µg Clone Number: Aliases:FLJ22252 antibody; SOX17 antibody; SOX17_ antibody; SRY (sex determining region Y) box 17 antibody; SRY box 17 antibody; SRY related HMG box transcription factor SOX17 antibody; Transcription factor SOX-17 antibody; Transcription factor SOX17 antibody; VUR3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H6I2 Immunogen:Recombinant Transcription factor SOX-17 protein (177-414AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as transcription regµLator that binds target promoter DNA and bends the DNA. Binds to the sequences 5\'-AACAAT-\'3 or 5\'-AACAAAG-3\'. ModµLates transcriptional regµLation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regµLation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SOX17 Research Areas:Epigenetics and Nuclear Signaling; Developmental biology; Stem cells