ELISA METTL14 Antibody, HRP

Quantity :50µg Clone Number: Aliases:KIAA1627 antibody; MET14_ antibody; Methyltransferase like 14 antibody; Methyltransferase-like protein 14 antibody; METTL14 antibody; N6-adenosine-methyltransferase subunit METTL14 antibody; OTTHUMP00000219837 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9HCE5 Immunogen:Recombinant N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regµLator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5\\\'-[AG]GAC-3\\\' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regµLates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regµLator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts resµLts in transcript destabilization (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:METTL14 Research Areas:Cell biology