ELISA VPS51 anti-

Quantity :50µL Clone Number: Aliases:ANG2 antibody; ANG3 antibody; Another new gene 2 protein antibody; C11orf3 antibody; chromosome 11 open reading frame 2 antibody; Fat free homolog antibody; ffr antibody; FFR_ antibody; FFR|FLJ13879 antibody; FLJ36472 antibody; Protein fat-free homolog antibody; Vacuolar protein sorting 51 homolog antibody; VPS51 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UID3 Immunogen:Recombinant Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000 Background:Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VPS51 Research Areas:Signal transduction