ELISA SPC25 Antibody, HRP

Quantity :50µg Clone Number: Aliases:AD024 antibody; hSpc25 antibody; Kinetochore protein Spc25 antibody; SPBC25 antibody; SPC25 antibody; SPC25_ antibody; spindle pole body component 25 homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9HBM1 Immunogen:Recombinant Kinetochore protein Spc25 protein (1-224AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14699129, PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubµLe binding sites in the outer plate of the kinetochore (PubMed:14738735, PubMed:14699129). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubµLes and may allow the NDC80 complex to track depolymerizing microtubµLes (PubMed:23085020). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SPC25 Research Areas:Epigenetics and Nuclear Signaling; Cell biology