ELISA TRPV4 anti-

Quantity :50µL Clone Number: Aliases:BCYM3 antibody; CMT2C antibody; HMSN2C antibody; osm 9 like TRP channel 4 antibody; Osm-9-like TRP channel 4 antibody; OSM9 like transient receptor potential channel 4 antibody; Osmosensitive transient receptor potential channel 4 antibody; OTRPC 4 antibody; OTRPC4 antibody; SMAL antibody; SPSMA antibody; SSQTL1 antibody; Transient receptor potential cation channel subfamily V member 4 antibody; Transient receptor potential protein 12 antibody; TRP 12 antibody; TRP12 antibody; TRPV 4 antibody; TrpV4 antibody; TRPV4_ antibody; Vanilloid receptor like channel 2 antibody; Vanilloid receptor like protein 2 antibody; Vanilloid receptor related osmotically activated channel antibody; Vanilloid receptor-like channel 2 antibody; Vanilloid receptor-like protein 2 antibody; Vanilloid receptor-related osmotically-activated channel antibody; VR 4 antibody; VR OAC antibody; VR-OAC antibody; VR4 antibody; VRL 2 antibody; VRL-2 antibody; VRL2 antibody; VROAC antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9HBA0 Immunogen:Recombinant Transient receptor potential cation channel subfamily V member 4 protein (1-230AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellµLar Ca2+ potentiates currents. Channel activity seems to be regµLated by a calmodµLin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellµLar barriers. Acts as a regµLator of intracellµLar Ca2+ in synoviocytes. Plays an obligatory role as a molecµLar component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimµLation in synoviocytes and also regµLates production of IL-8. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRPV4 Research Areas:Neuroscience