ELISA TXNIP Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:EST01027 antibody; HHCPA78 antibody; THIF antibody; Thioredoxin binding protein 2 antibody; Thioredoxin interacting protein antibody; Thioredoxin-binding protein 2 antibody; Thioredoxin-interacting protein antibody; TXNIP antibody; TXNIP_ antibody; UpregµLated by 1,25 dihydroxyvitamin D 3 antibody; VDUP1 antibody; Vitamin D3 up-regµLated protein 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9H3M7
Immunogen:Recombinant Thioredoxin-interacting protein (299-381AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecµLe between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:TXNIP
Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism; Signal transduction
Référence interne:
CSB-PA880966LC01HU
URL de site web:
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