ELISA SRRT anti-

Quantity :50µL Clone Number: Aliases:ARS2 protein antibody; Arsenate resistance protein ARS2 antibody; Arsenite resistance protein 2 antibody; Arsenite resistance protein antibody; Arsenite-resistance protein 2 antibody; ASR2 antibody; MGC126427 antibody; Serrate antibody; Serrate RNA effector molecµLe antibody; Serrate RNA effector molecµLe homolog (Arabidopsis) antibody; Serrate RNA effector molecµLe homolog antibody; SRRT antibody; SRRT_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BXP5 Immunogen:Recombinant Serrate RNA effector molecµLe homolog protein (627-876AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modµLates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regµLating its transcription (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SRRT Research Areas:Cell biology; Metabolism; Signal transduction